Trinitrate (Nitroglycerine) on Raynaud's Disease and Raynaud's Phenomenon
نویسندگان
چکیده
The authors investigated the effect of repeated inunction with 2 per cent glyceryl trinitrate in lanolin on the blood flow and skin temperature of the extremities in 14 cases of Raynaud's disease and in 8 cases in which Raynaud's phenomenon was associated with such vascular diseases as acrosclerosis (3 cases), chronic occlusive disease of the arteries (3 cases), occupational disease of the arteries (1 case) and livedo reticularis (1 case). The inunction almost invariably caused an increase in the blood flow and in the skin temperature of the digits in the 14 cases of Raynaud's disease.
منابع مشابه
The effect of local application of glyceryl trinitrate (nitroglycerine) on Raynaud's disease and Raynaud's phenomenon; studies on blood flow and clinical manifestations.
The authors investigated the effect of repeated inunction with 2 per cent glyceryl trinitrate in lanolin on the blood flow and skin temperature of the extremities in 14 cases of Raynaud's disease and in 8 cases in which Raynaud's phenomenon was associated with such vascular diseases as acrosclerosis (3 cases), chronic occlusive disease of the arteries (3 cases), occupational disease of the arte...
متن کاملObjective relief of vasospasm by glyceryl trinitrate in secondary Raynaud's phenomenon.
An objective response to topical glyceryl trinitrate was shown by digital plethysmography in a study of 17 patients with Raynaud's phenomenon. Improvement was significant (P less than 0.005) in those in whom the disease was secondary to an underlying connective tissue disorder. The response suggests that the effect of this drug is mediated locally.
متن کاملA retrospective clinical analysis of medical treatments used for symptomatic relief of Raynaud's phenomenon in children at Royal Liverpool Children's Hospital, UK
Background Literature on treatment of Raynaud's phenomenon (RP) in the paediatric age group is scarce, and practice varies. We completed a retrospective analysis of patients with RP treated by paediatric rheumatologists at Royal Liverpool Children's Hospital to assess clinical response to medical treatments including calcium channel blockers (nifedipine and amlodipine) and Glyceryl trinitrate (...
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FROM January 1920 to December 1945, inclusive, Raynaud's disease, Raynaud's phenomenon, or questionable Raynaud's disease was diagnosed in 756 female patients at the Mayo Clinic. Data gleaned from a critical review of the clinical records and from follow-up questionnaires constitute the basis for the present report. In 1945 Hines and Christensen,' in a similar study of Raynaud's disease among m...
متن کاملRaynaud's Disease Among Woinen and Girls
FROM January 1920 to December 1945, inclusive, Raynaud's disease, Raynaud's phenomenon, or questionable Raynaud's disease was diagnosed in 756 female patients at the Mayo Clinic. Data gleaned from a critical review of the clinical records and from follow-up questionnaires constitute the basis for the present report. In 1945 Hines and Christensen,' in a similar study of Raynaud's disease among m...
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